At GenapSys we are working to power the world of healthcare and diagnostics with advanced DNA sequencing technology. Our proprietary technology integrates advanced electronics, molecular biology, fluidics and data analytics and machine learning to dramatically reduce cost of ownership and operating expenses for DNA and RNA sequencing.
Our team brings together an incredibly diverse and multidisciplinary set of backgrounds and skills – from electrical and mechanical engineers, to physicists, chemists, microfluidic engineers, molecular biologists, bioinformaticians, mathematicians and more. Together we will advance scientific and medical knowledge and improve human health through transformative DNA sequencing technologies. We are working cross functionally to make a great impact in the world – join us on that mission!
We are looking for a Bioinformatics Scientist who can develop, maintain, and evolve novel next generation sequence analysis software and pipelines with a focus on run assessment, data quality, knowledge integration, data interpretation, hypothesis generation and testing, as well as common sequence alignment algorithms/tools and NGS applications. Demonstrable experience using data mining and analysis tools to identify dominant patterns in next generation sequence datasets to diagnose instrument performance. If these challenges seem exciting and you fit the requirement outlined below - please apply!
Play a key role in developing comprehensive bioinformatic analysis solutions for the Genapsys NGS data
Perform detailed bioinformatics analysis including reference genome alignment, targeted sequencing, mapping, annotation and variant calling using a variety of data sets generated by the Genius platform as well as other NGS systems
Analyze sequencing datasets to assess quality of experimental data and provide feedback to signal processing and algorithm teams for further improvement
Monitor data integrity and quality and alert team members when inconsistencies arise and help troubleshoot the problem
Actively participate in the ongoing development of the Genapsys sequencing technology.
PhD or MS in Bioinformatics, Computer Science, Computational Biology, Electrical Engineering/Signal processing or a related field with > 5 years’ experience
Hands-on experience with bioinformatics methods appropriate for NGS applications (targeted sequencing, RNASeq, CHiPSeq, and de novo genome assembly)
Hands-on experience with genome alignment, mapping, variant calling and annotation (e.g. BWA, Bowtie, STAR, GATK, samtools, bcftools)
Deep understanding of next generation sequence sequencing methods, quality scores and their interpretation
Experience with open source bioinformatics and genome analysis tools (e.g. samtools, bedtools)
Experience designing and developing research and/ or production grade bioinformatics pipeline solutions for NGS applications
Solid experience in Python, and demonstrated experience in other programming/scripting languages: R, Bash
Ability to work collaboratively with primary analysis team, software developers, and the pipeline team
Prior experience in a NGS company or NGS research lab is a plus
Prior experience in developing NGS pipelines is a plus
Ability to apply advanced statistical methods, machine learning, data science to molecular biology
About GenapSys, Inc.
GenapSys is introducing a new era of applied genomic testing with our GENIUS ™ DNA Sequencing System sequencer. We developed an innovative system to democratize access to genetic testing for everyone. As we enter a multi-decade era based on the use of genomics, many industries will be revolutionized such as drug discovery and diagnostics. We have developed a cost-effective, affordable, easy-to-use genetic testing system based on a proprietary technology.
Our goal is simple: Impact. We believe the tool that can read the code of DNA easily, inexpensively and accessible to anyone, is one of the most meaningful devices of the 21st century and this technology will dramatically shape the lives of both current and future generations.
We are looking for talented, hard-working, and passionate individuals to develop GenapSys’ ground-breaking DNA sequencing technologies and systems. Our work is multidisciplinary ranging from applied physics and engineering to life science and bioinformatics. We are looking for experts in circuit design, biosensors, fluidics, device design, DNA sequencing and surface chemistries, as well as business & R&D management.
We are seeking self-starters to jo...in us on our mission to change the world of healthcare and diagnostics through accessible genomic information!